1Departments of Hospital Pathology, The Catholic University of Korea, College of Medicine 2Departments of Orthopedic Surgery, The Catholic University of Korea, College of Medicine
Corresponding Author:
Jea na Kim ,Tel: +82-32-340-7091, Fax: +82-32-340-2219, Email: Jeanakim@catholic.ac.kr
Received: November 15, 2009; Accepted: December 12, 2009.
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ABSTRACT
Leiomyosarcoma of somatic soft tissue is a rare tumor compared with retroperitoneal lesion. We report a case of a
leiomyosarcoma of the somatic soft tissue in a 66-year-old man. He presented as an enlarging mass in the left thigh for
eight months. Radiologic examinations revealed a well defined round mass, suspicious of benign tumor, such as
hemangioma or leiomyoma. He underwent surgical resection. The mass was 3.0 cm in diameter, and it was confined
within adductor longus muscle without any connection to adjacent neurovascular bundles. Histologic examination showed
moderately cellularity and focal marked atypia with a fascicular growth pattern of spindle cells showing blunt ended
nuclei. In addition, the proliferation index was 2~3% by immunohistochemistry using monoclonal antibody MIB-1. But only
one definite microscopic mitotic feature was found. Although it showed low mitotic activity without necrosis, this case was
diagnosed leiomyosarcoma according to marked cellular atypism.
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