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Korean Journal of Clinical Oncology > Article
Korean J Clin Oncol. 2009;5(2): 65-68.         doi: https://doi.org/10.14216/kjco.09015
Leiomyosarcoma of Somatic Soft Tissue: A Case Report
Kyung ji Lee1, An hi Lee1, Jea na Kim1, Hyoung min Kim2, Kyo Young Lee2
1Departments of Hospital Pathology, The Catholic University of Korea, College of Medicine
2Departments of Orthopedic Surgery, The Catholic University of Korea, College of Medicine
체성 연부 조직에 생긴 평활근육종: 1예 보고
이경지1, 이안희1, 김진아1, 김형민2, 이교영2
1가톨릭대학교 의과대학 병원병리학교실
2가톨릭대학교 의과대학 정형외과학교실
Corresponding Author: Jea na Kim ,Tel: +82-32-340-7091, Fax: +82-32-340-2219, Email: Jeanakim@catholic.ac.kr
Received: November 15, 2009;  Accepted: December 12, 2009.
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Leiomyosarcoma of somatic soft tissue is a rare tumor compared with retroperitoneal lesion. We report a case of a leiomyosarcoma of the somatic soft tissue in a 66-year-old man. He presented as an enlarging mass in the left thigh for eight months. Radiologic examinations revealed a well defined round mass, suspicious of benign tumor, such as hemangioma or leiomyoma. He underwent surgical resection. The mass was 3.0 cm in diameter, and it was confined within adductor longus muscle without any connection to adjacent neurovascular bundles. Histologic examination showed moderately cellularity and focal marked atypia with a fascicular growth pattern of spindle cells showing blunt ended nuclei. In addition, the proliferation index was 2~3% by immunohistochemistry using monoclonal antibody MIB-1. But only one definite microscopic mitotic feature was found. Although it showed low mitotic activity without necrosis, this case was diagnosed leiomyosarcoma according to marked cellular atypism.
Keywords: Soft tissue | Leiomyosarcoma
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