| The Significance of PET-CT for detection of distant metastasis
in advanced gastric cancer with perigastric infiltration |
| Cheong Ah Oh, Dae Hoon Kim, Seung Jong Oh, Young Sik Bae, Min Gew Choi, Jae Hyung Noh, Tae Sung Sohn, Jae Moon Bae, Sung Kim |
| Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
| 수술 전 복부 전산화 단층촬영에서 위 주위 조직 침윤을 보이는 진행성 위암에서 PET-CT의 의의 |
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오정아, 김대훈, 오승종, 배영식, 최민규, 노재형, 손태성, 배재문, 김성 |
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성균관대학교 의과대학 삼성서울병원 외과학 교실 |
| Corresponding Author:
Tae Sung Sohn ,Tel: +82-2-3410-0498, Fax: +82-2-3410-6981, Email: ts.sohn@samsung.com |
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Received: November 20, 2010; Accepted: December 23, 2010. |
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| ABSTRACT |
Purpose: The aim of this study was to evaluate the diagnostic value of 18F-FDG PET for detecting nodal metastasis,
distant metastasis and peritoneal metastasis in patients with advanced gastric cancer with perigastric fat infiltration
and to identify histopathologic parameters that may affect FDG uptake of primary tumor and regional LN among
these patients
Materials and
Methods: From September 2006 to August 2007, 101 patients diagnosed with gastric cancer by
gastrofiberscopic biopsy and shown as having findings of perigastric fat infiltration on CT were enrolled. The
sensitivities, specificities, positive predictive value, and negative predictive value of PET-CT were evaluated in the
detection of nodal metastasis and peritoneal metastasis. In cases with perceptible FDG uptake in primary tumor
and regional lymph node, the standardized uptake value (SUV) was calculated. The clinicopathologic results such
as depth of invasion (T stage), tumor size, lymph node metastasis, tumor histological type, Lauren classification
were reviewed.
Results: PET-CT had a lower sensitivity in detecting of nodal metastasis and peritoneal metastasis. Borrmann type
and tumor diameter was related to the degree of FDG uptake in primary tumor and regional lymph node.
Conclusions: It might be concluded that PET-CT has little role in the detection of nodal metastasis and peritoneal
metastasis due to its low sensitivity. |
| Keywords:
Gastric cancer | PET-CT | FDG uptake |
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