The Influence of Proximal Resection Margin in
Adenocarcinoma of the Gastroesophageal Junction on survival |
Cheon Soo Park, Tae Hwan Kim, Beom Su Kim, Kab Choong Kim, Sung Tae Oh, Byung Sik Kim, Jeong Hwan Yook |
Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea |
위식도접합부 선암에서 근위부 절제연의 길이가 예후에 미치는 영향 |
박천수, 김태환, 김범수, 김갑중, 오성태, 김병식, 육정환 |
울산대학교 의과대학 서울아산병원 외과학교실 |
Corresponding Author:
Jeong Hwan Yook ,Tel: +82-2-3010-3496, Fax: +82-2-3010-6701, Email: jhyook@amc.seoul.kr |
Received: May 20, 2010; Accepted: June 23, 2010. |
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ABSTRACT |
Purpose: To determine the length of proximal resection margin for patients with adenocarcinoma of the
gastroesophageal junction(GEJ).
Materials and Methods: We reviewed retrospectively the medical records of the 289 patients who underwent
surgery for adenocarcinoma of GEJ in our institution between Janury 2001 and December 2003.
Result: The 289 patients who underwent surgery for adenocarcinoma of GEJ were divided on T stage, below T1
group(T1,n=66) and above T2 group(T2-4, n=223). We studied the influence of proximal resection margin in
adenocarcinoma of the GEJ on survival. In T1(n=66) group, univariate analysis revealed no influence of proximal
resection margin in adenocarcinoma of GEJ on survival. In T2-4(n=223) group, univariate analysis revealed
influence of proximal resection margin on survival ; 0.5cm, 2.0cm, 3.0cm, 3.5cm, 4.0cm. Multivariate
analysis show that only influence of proximal resection margin on survival; 0.5cm (p=0.009, HR:2.232, 95%
CI:1.218-4.091)
Conclusion: We should be undergoing surgery for T2-4 gastric adenocarcinoma of GEJ with safely proximal
resection margin; >0.5cm for survival improvement. |
Keywords:
Adenocarcinoma of the Gastroesophageal Junction | Length of Proximal Resection Margin |
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