| Prognostic Factors of Stage II Rectal Cancer |
| Bo Hyun Hwang1, Ji Won Park2, Sung Chan Park2, Sun Young Kim2, Ji Yeon Baek2, Dae Yong Kim2, Hee Jin Chang2, Hyo Sung Choi2, Jae Hwan Oh2 |
1Department of surgery, Seoul National University College of Medicine, Seoul, Korea
2Center for Colorectal Cancer, Research Institute & Hospital, National Cancer Center, Goyang, Korea |
| 2기 직장암의 예후인자 |
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황보현1, 박지원2, 박성찬2, 김선영2, 백지연2, 김대용2, 장희진2, 최효성2, 오재환2 |
1서울대학교 외과학교실
2국립암센터 대장암센터 |
| Corresponding Author:
Jae Hwan Oh ,Tel: +82-31-920-2798, Fax: +82-31-920-0149, Email: jayoh@ncc.re.kr |
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Received: September 23, 2011; Accepted: October 20, 2011. |
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| ABSTRACT |
|
Background : In stage II rectal cancer, it has remained controversial whether patients get the benefit from adjuvant
treatment after curative resection. The aim of this study is to evaluate the prognostic factors of stage II rectal
cancer.
Methods : From October 2000 to December 2008, 200 patients with stage II rectal cancer underwent surgery at
National Cancer Center. Univariate and multivariate survival analyses were performed to determine the prognostic
factors in stage II rectal cancer.
Results : In stage II rectal cancer, 5-year overall survival and disease free survival were 89.2% and 89.0%,
respectively. For overall survival, there was no significant prognostic factor in multivariable analysis. For diseasefree
survival, tumor differentiation and circumferential resection margin were significant prognostic factors in
multivariable analysis.
Conclusion : Tumor differentiation and circumference resection margin are independent prognostic factors in
disease free survival of stage II rectal cancer. Adjuvant treatment may be considered in patients with these factors. |
| Keywords:
rectal cancer | stage II | prognostic factor | survival |
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