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Korean Journal of Clinical Oncology > Article
Korean Journal of Clinical Oncology 2011;7(1): 60-65.
유방암 환자의 액와 림프절 전이에 대한 수술 전 초음파 검사의 진단 유용성
한동일1, 곽금희1, 한세환1, 김지영2, 박경미3, 조현진1, 양근호1, 배병노1, 김기환1
1인제 대학교 상계백병원 외과학교실
2인제 대학교 상계백병원 영상의학교실
3인제 대학교 상계백병원 병리학교실
Diagnostic value of preoperative sonographic evaluation for axillary lymph node metastases in breast cancer patients
Dongil Han1, Geumhee Gwak1, Sehwan Han1, Ji-Young Kim2, Kyeongmee Park3, Hyunjin Cho1, Geunho Yang1, Byungnoe Bae1, Kihwan Kim1
1Department of Surgery, Inje University Sangge-Paik Hospital
2Department of Radiology, Inje University Sangge-Paik Hospital
3Department of Pathology, Inje University Sanggye Paik Hospital
Corresponding Author: Geumhee Gwak ,Tel: +82-2-950-1938, Fax: +82-2-933-9389, Email: gsrad@hanmail.net
Received: May 23, 2011;  Accepted: June 20, 2011.
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ABSTRACT
Purpose: The aim of this study was evaluate predictive value of preoperative sonography for the evaluation of axillary lymph node metastases in breast cancer patients. Materials and
Methods: The study included 226 patients who underwent curative surgery between Jan. 2008 ~ Dec. 2010 at Inje University Sanggye Paik Hospital. We analyzed preoperative sonographic findings of axillary lymph nodes and compared the finding with postoperative histologic results of axillary lymph nodes evaluation.
Results: When we compared preoperative sonographic evaluation of metastatic lymph node with final histological results, the sensitivity of sonographic evaluation was 81.3% and specificity was 77.5%. False positive rate was 10.7% and false negative rate was 35.8%. The accuracy of preoperative sonographic evaluation of lymph node metastasis was 78.7%. Primary tumor size was the only significant predictive factor for lymph node metastasis on multivariate analysis.
Conclusion: preoperative sonographic evaluation of axillary lymph node had limited value with moderate accuracy. High false-negative rate of preoperative sonography indicates that preoperative sonography cannot replace intraoperative sentinel node evaluation at this stage.
Keywords: axillary lymph nodes metastases | breast ca | breast sonography
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