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Korean J Clin Oncol. 2005;1(1): 27-32.
Current status of chemotherapy for gastric cancer
Cho Hyun Park
Department of Surgery, Kang-Nam St. Mary's Hospital, The Catholic University of Korea
위암 항암요법의 최신지견
가톨릭대학교 의과대학 외과학교실
Corresponding Author: Cho Hyun Park ,Tel: 82-2-590-2727, Fax: 02-595-2992, Email: chpark@catholic.ac.kr
Received: May 30, 2005;  Accepted: June 30, 2005.
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Currently, standard chemotherapy for the treatment of gastric cancer still remains controversial. However, recent series of meta-analysis of adjuvant chemotherapy have shown a small, but statistically significant reduction in risk of death. Moreover, newly developed chemotherapeutic agents for gastric cancer are reported higher response rate than conventional drugs even in a single drug treatment. Therefore, we are awaiting for the result of well-designed large, prospect clinical trials. In this review, recent studies dealing with the chemotherapy of advanced gastric cancer are summarized. While the efficacy of most treatment regimens is only limited, tailored therapy for patient based on clinico-pathological findings and/or molecular biology can improve the treatment result in the near future.
Keywords: Advanced gastric cancer | Chemotherapy
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