| What is an optimal nutritional index for hepaocellular carcinoma during early perioperative period after hepatic resection? |
| Sang Hwa Kim1, Jin Hong Lim1,3, Sung Hoon Kim2, Su Ji Lee1,3, Ho Sun Lee3, Jae Gil Lee1,3, Choong Bai Kim1,3, Kyung Sik Kim1,3 |
1Dept. of Surgery, Severance Hospital, Yonsei University College of Medicine, Dept. of Surgery, Wonju Christian Hospital, Wonju, Korea
2Yonsei University Wonju College of Medicine, Wonju, Korea
3Nutritional Support Team, Severance Hospital, Korea |
| Corresponding Author:
Kyung Sik Kim ,Tel: +82-2-2228-2125, Fax: +82-2-313-8289, Email: kskim88@yuhs.ac |
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Received: September 10, 2012; Accepted: December 14, 2012. |
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| ABSTRACT |
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After hepatic resection, a synthetic liver function is often deteriorated, and ascites have been occasionally developed. Because of these limitations, this study is designed to validate the optimal nutritional index. We retrospectively reviewed medical records of sixty-five patients who underwent hepatectomy for hepatocellular carcinoma. Body weight, Body Mass Index (BMI) and laboratory parameters were compared at preoperative day and postoperative day 7. Patients consist of fifty-two males and thirteen females and average age is 56.2±9.9 years old. Forty-four patients had resected more than three segments, and twelve had resected 2 segments and nine had resected only one segment or received a wedge resection. According to preoperative BMI, there were two underweight (BMI < 18.5), twenty-two normal, nineteen overweight, and twenty-two obese (BMI>=27.5). After the surgery, lymphocyte count, total protein, albumin, BUN, Cholesterol, Prealbumin statistically significantly decreased, while WBC (5642±1831 Vs. 7149±3069), CRP (2.98±4.78 Vs. 25.69±22.23) statistically significantly increased (p=0.00 & p=0.00).However, BMI and change in Body weight do not show statistically significant data (p=1.91, p=8.23). The degree of inflammation may have a significant influence in nutrition evaluation scale. Therefore, a new method of nutritional evaluation that can adjust degree of inflammation is needed to accurately evaluate the nutrition scale after hepatectomy. |
| Keywords:
Hepatectomy | Nutritional assessment | Nutritional index | Prealbumin |
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